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Whether you are looking for a reliable supplier of high-quality DNA products or require assistance in getting your genetic payload efficiently delivered to the target cells, 4basebio has the technologies, expertise and capabilities to assist you with your therapy development plans. Please contact us at services@4basebio.com for any questions around our 4BBTM service offering. We also make our 4BBTM technology accessible through our gene therapy and vaccine licensing programs.

4basebio offers access to its 4BB™ synthetic DNA technologies, hpDNA™ (linear closed) and osDNA™ (linear open) opDNA™ (linear partially open and oeDNA™ (linear open), through supply and manufacturing services.

  • RUO, RUO-HQ and GMP-Compliant grades available
  • Batch scale from µg levels to multiple gram
  • Multiple constructs in parallel available
  • Rapid turnaround

Off the shelf Rep-Cap, Helper and reporter AAV constructs for a range of serotypes, and reporter mRNA constructs, are also available.

Learn more about our DNA manufacturing in our video:

4basebio offers mRNA supply services, using our synthetic DNA templates and IVT process.

  • RUO, RUO-HQ and GMP-Compliant grades available
  • Batch scale from µg levels to multiple gram
  • Multiple constructs in parallel available
  • Rapid turnaround

Learn more about our mRNA services in our video:

4basebio offers small scale AAV production, characterisation and purification with rapid turnaround for in vitro and in vivo experiments.

Learn more about our AAV production in our video:

4basebio offers access to its targeted non-viral delivery platform, Hermes™, through development and production services of nanoparticles targeting specific cells or tissues of interest.

  • In vitro potency optimisation and nanoparticle characterisation
  • Packaging of DNA, RNA, protein (or combination thereof)
  • Development of cell specific targeting and in vitro validation
  • Encapsulation of custom payloads are existing Hermes™ particles
  • In vitro and in vivo validation services
  • Manufacture for pre-clinical in vivo studies

For more information and how our technologies can help you, please contact us

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